| Source: | Human cells |
| Description: | Recombinant Mouse Growth Differentiation Factor 15 is produced by our Mammalian expression system and the target gene encoding Ser189-Ala303 is expressed with a 8His, Flag tag at the N-terminus. |
| Accession: | Q9Z0J7 |
| Known As: | Growth Differentiation Factor 15, Macrophage inhibitory cytokine 1, GDF-15, MIC-1, NAG-1, PLAB, PTGFB |
| Predicted Mol Mass: | 16.9 Kda |
| Apparent Mol Mass: | 14-16 KDa, reducing conditions |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| Reconstitution: | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Shipping: | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage: | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Background: | Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenitors and introduced as a putative placental mediator of embryonic development. GDF15 has recently gained scientific and translational prominence with the discovery that its receptor is a GFRAL-RET heterodimer of which GFRAL is expressed solely in the hindbrain. |
重组小鼠生长分化因子15(GDF-15)
¥1,600.00
规格: 10μg
英文名字：Growth Differentiation Factor 15(GDF-15),Mouse,Recombinant(N-8His-Flag)
质量标准：>95%,BR