辅酶A钠盐水合物；Coenzyme A sodium salt hydrate cofactor for acyl transfer；
分子式：C21H36N7O16P3S · xNa+ · yH2O;分子量：767.53 (anhydrous free acid basis)
外观：类白色粉末
纯度：≥85% (spectrophotometric assay)
溶解性：H2O: soluble 50 mg/mL clear, colorless to faintly yellow
用途：
Coenzyme A is suitable for use in:
• gylcerolipid biosynthesis in porcine adipose tissue
• an assay to measure the level of Alpha-methylacyl-CoA racemase (AMACR) in human blood samples using a nanoparticle electrochemical biosensor
• chloramphenicol acetyltransferase (CAT) assay
• the synthesis of palmitoyl-CoA, which is required for palmitoylation and activation of proteins for regulated membrane fusion
生物活性
Coenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. In the presence of CoASH, organic carboxylic acids form acyl-CoA thioesters, which facilitates enzyme recognition. The acyl-CoA formed from xenobiotic carboxylic acids can add to the compound′s toxicity, which can lead to cellular metabolic dysfunction. It is involved in the oxidation of pyruvate in the Kreb′s cycle.
储存条件：−20°C