重组人肿瘤坏死因子受体I型(TNFRI,Human)

¥800.00

规格: 10μg

TNF R I, Human;TNF R I, Human/TNFRSF1A
简介:
TNF Receptor Type I, is also known as TNF R-p55/p60 and TNFRSF1A. It is a type I transmembrane protein member of the TNF receptor superfamily. It is expressed in most cell types. Binding of either TNF-α or TNF-β to TNF-R1 initiates a signal transduction pathway that results in the activation of the transcription factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells, induce apoptosis. TNF-R1 is essential for proper development of lymph node germinal centers and Peyer’s patches and for combating intracellular pathogens such as Listeria. It is stored in the Golgi and translocates to the cell surface following proinflammatory stimuli.
别名:Soluble Tumor Necrosis Factor type I, TNFRSF1A, TNFAR, TNF-R55, TNFR60, p55, CD120a
性状描述:
Species:……………………………Human
Source:……………………………CHO
Measured Molecular Weight:……28~35 kDa, observed by reducing SDS-PAGE.
Purity:………………………………> 95% as analyzed by SDS-PAGE.
Formulation:………………………Lyophilized after extensive dialysis against PBS.
Reconstitution:……………………Reconstituted in ddH2O or PBS at 100 μg/ml.
Endotoxin Level:…………………< 0.2 EU/μg, determined by LAL method.
Sequence:

DSVCPQGKYI HPQNNSICCT KCHKGTYLYN DCPGPGQDTD
CRECESGSFT ASENHLRHCL SCSKCRKEMG QVEISSCTVD
RDTVCGCRKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE
KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE
N
储存条件:
Lyophilized recombinant Human TNF Receptor Type I remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, Human TNF Receptor Type I should be stable up to 1 week at 4°C or up to 2 months at -20°C.

运输条件:

2~8℃运输
生物活性:
ED50 < 50 ng/ml, measured in a cell proliferation assay using 929 cells in the presence of 1 ng/ml human TNF-α.
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用途及描述:科研试剂,广泛应用于分子生物学,药理学等科研方面,严禁用于人体。

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规格

10μg

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