别名：TRAIL Receptor-2; DR5; TRAIL R2; KILER; TRICK2A; TRICK
基本信息：
| Source | E. coli. |
| Species | Human |
| Tag | Tag free |
| Description | Human TRAILR2/TNFRSF10B (Glu52-Ser183) |
| Accession# | O14763 |
| Predicted molecular mass | ~14.8 kDa. It is composed of one non-glycosylated polypeptide chain containing 132 amino acids. |
| Appearance | White powder, Colorless clear liquid after reconstitution |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining) |
| Endotoxin | < 0.1 EU/μg |
| Activity | rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24-hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed. |
| Formulation | 0.2 μm-filtered solution containing 20 mM PB, with 150 mM NaCl, pH 7.4. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. 细胞因子溶解、稀释、保存可使用即用型专用溶剂套装—PWL240（1mL无菌水+10mL稀释液） |
| Shipping | Wet ice (seasonal) |
| Storage&Stability
|
36 months at -20°C to -80°C in lyophilized state
6 months at -20°C to -80°C under sterile conditions after reconstitution 7-10 days at 2°C to 8°C under sterile conditions after reconstitution Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
数据展示：
SDS-PAGE
Recombinant Human TRAILR2/TNFRSF10B (Cat. No. MGC175)SDS-PAGE under reducing (R) & Non-reducing conditions.