二氢细胞松弛素B

二氢细胞松弛素；Dihydrocytochalasin B
分子式：C₂₉H₃₉NO₅ 分子量：481.62
物理性状及指标：
外观：……………………白色结晶
熔点：……………………203~205°C
溶解性：…………………溶于有机溶剂如乙醇(20mg/ml)DMSO(20mg/ml)
炽灼残留：………………<0.1%
纯度：……………………>98%
重金属：…………………<0.002%
生物活性
Dihydrocytochalasin B (DCB) is a member of the cytochalasin mycotoxin family that inhibits actin assembly. It blocks cleavage furrow formation and cytokinesis in synchronous HeLa cells at a concentration of 10 μM. DCB induces tetraploidy and arrests the cell cycle indefinitely in the G1 phase in REF-52 cells. It also increases the drug sensitivity of multidrug resistant SKVLB1 cells to paclitaxel (Item No. MB1178) and doxorubicin (Item No.MB1087)in vitro.

用途及描述：

科研试剂.用于膜蛋白的溶解，透化细胞和细胞核膜

储存条件：

-15~-20°C